How to replace the radiator for the 4.3, 4.8, 5.3, and 6.0L engines on 2006 GMC Sierra 1500?

To install the radiator in place of the radiators, first of all remove the cooling fan and shroud and then remove the radiator outlet hose that belongs to the engine. Disassemble the oil cooler lines, when in case, remove the radiator bolts and extract the radiator. Uninstall then repeat steps in reverse order.

OEM 2006 GMC Sierra 1500 Radiator

Cooling Radiator

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12 Radiators found

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2006 GMC Sierra 1500 Radiator Part Number: 20935856
$494.57 MSRP: $742.60
You Save: $248.03 (34%)
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Product Specifications
- Other Name: Radiator Assembly; Radiator, Radiator
- Replaces: 10387446, 15841573, 25833292
- Item Weight: 16.20 Pounds
- Item Dimensions: 47.4 x 25.2 x 7.4 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 20935856
- Warranty: This genuine part is guaranteed by GM's factory warranty.
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Fits the following 2006 GMC Sierra 1500 Submodels:
- Denali, SL, SLE, SLT, WT, XFE | 8 Cyl 5.3 L FLEX, 8 Cyl 5.3 L GAS, 8 Cyl 6.0 L GAS
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2006 GMC Sierra 1500 Radiator Part Number: 15841574
$251.25 MSRP: $375.57
You Save: $124.32 (34%)
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Product Specifications
- Other Name: Radiator, Radiator
- Replaces: 15252624, 15193114
- Item Weight: 15.30 Pounds
- Item Dimensions: 47.7 x 7.6 x 25.9 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 15841574
- Warranty: This genuine part is guaranteed by GM's factory warranty.
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Fits the following 2006 GMC Sierra 1500 Submodels:
- Base, Denali, SLE, SLT, WT | 8 Cyl 6.0 L GAS, 8 Cyl 6.2 L GAS
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2006 GMC Sierra 1500 Radiator Part Number: 22840115
$293.04 MSRP: $438.04
You Save: $145.00 (34%)
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Product Specifications
- Other Name: Radiator Assembly; Radiator, Radiator
- Replaces: 15124631, 15797140, 15841569, 20935857
- Item Weight: 21.20 Pounds
- Item Dimensions: 47.8 x 24.5 x 8.3 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 22840115
- Warranty: This genuine part is guaranteed by GM's factory warranty.
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Fits the following 2006 GMC Sierra 1500 Submodels:
- Base, Denali, HT, Hybrid, SL, SLE, SLT, WT, XFE | 6 Cyl 4.3 L GAS, 8 Cyl 4.8 L FLEX, 8 Cyl 5.3 L FLEX, 8 Cyl 6.0 L FULL HYBRID EV-FLEX (FHEV), 8 Cyl 6.0 L FULL HYBRID EV-GAS (FHEV), 8 Cyl 6.0 L GAS, 8 Cyl 6.2 L FLEX
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2006 GMC Sierra 1500 Radiator Part Number: 19256745
$336.66 MSRP: $477.13
You Save: $140.47 (30%)
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Product Specifications
- Other Name: Radiator Assembly; Radiator, Radiator
- Replaces: 15124630, 15797139, 15841568
- Item Weight: 17.40 Pounds
- Item Dimensions: 49.0 x 26.6 x 8.0 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 19256745
- Warranty: This genuine part is guaranteed by GM's factory warranty.
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Fits the following 2006 GMC Sierra 1500 Submodels:
- Denali, Hybrid, SL, SLE, SLT, WT | 8 Cyl 5.3 L FLEX, 8 Cyl 5.3 L FULL HYBRID EV-GAS (FHEV), 8 Cyl 5.3 L GAS, 8 Cyl 6.2 L GAS
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2006 GMC Sierra 1500 Radiator Part Number: 22840116
$317.71 MSRP: $450.27
You Save: $132.56 (30%)
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Product Specifications
- Other Name: Radiator Assembly; Radiator, Radiator
- Replaces: 15252625, 52473443, 15192412, 15193107, 15841570, 25811504, 22840118, 52486594, 52487603
- Item Weight: 24.50 Pounds
- Item Dimensions: 48.5 x 26.0 x 10.4 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 22840116
- Warranty: This genuine part is guaranteed by GM's factory warranty.
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Fits the following 2006 GMC Sierra 1500 Submodels:
- Base, C3, Denali, SLE, SLT, WT | 8 Cyl 6.0 L GAS
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2006 GMC Sierra 1500 Radiator Part Number: 22840117
$273.03 MSRP: $386.94
You Save: $113.91 (30%)
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Product Specifications
- Other Name: Radiator Assembly; Radiator, Radiator
- Replaces: 15124632, 15252638, 52473444, 15193108, 15841571, 52487604, 52486595
- Item Weight: 13.90 Pounds
- Item Dimensions: 48.1 x 26.1 x 7.9 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 22840117
- Warranty: This genuine part is guaranteed by GM's factory warranty.
More Info
Fits the following 2006 GMC Sierra 1500 Submodels:
- Base, C3, Denali, Hybrid, SL, SLE, SLT, WT, XFE | 6 Cyl 4.3 L GAS, 8 Cyl 4.8 L FLEX, 8 Cyl 4.8 L GAS, 8 Cyl 5.3 L FLEX, 8 Cyl 5.3 L FULL HYBRID EV-GAS (FHEV), 8 Cyl 5.3 L GAS, 8 Cyl 6.0 L FULL HYBRID EV-FLEX (FHEV), 8 Cyl 6.0 L GAS, 8 Cyl 6.2 L FLEX, 8 Cyl 6.2 L GAS
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2006 GMC Sierra 1500 Radiator Part Number: 15841572
$311.75 MSRP: $466.00
You Save: $154.25 (34%)
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Product Specifications
- Other Name: Radiator Assembly; Radiator, Radiator
- Replaces: 15124633, 15252642
- Item Weight: 12.90 Pounds
- Item Dimensions: 47.7 x 7.5 x 24.9 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 15841572
- Warranty: This genuine part is guaranteed by GM's factory warranty.
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Fits the following 2006 GMC Sierra 1500 Submodels:
- Base, SL, WT | 6 Cyl 4.3 L GAS
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2006 GMC Sierra 1500 Radiator Part Number: 15193110
$283.47 MSRP: $423.71
You Save: $140.24 (34%)
Product Specifications
- Other Name: Radiator Assembly; Radiator, Radiator
- Replaces: 15189403, 52486598
- Item Weight: 11.00 Pounds
- Item Dimensions: 39.5 x 25.2 x 7.1 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 15193110
- Warranty: This genuine part is guaranteed by GM's factory warranty.
More Info
Fits the following 2006 GMC Sierra 1500 Submodels:
- Base, HT, SL, SLE, SLT, WT | 8 Cyl 4.8 L GAS, 8 Cyl 5.3 L FLEX, 8 Cyl 5.3 L GAS
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2006 GMC Sierra 1500 Radiator Part Number: 15841575
$266.75 MSRP: $398.74
You Save: $131.99 (34%)
Product Specifications
- Other Name: Radiator Assembly; Radiator, Radiator
- Replaces: 15193109, 52473445, 15193115, 52486596
- Item Weight: 15.30 Pounds
- Item Dimensions: 7.3 x 48.8 x 26.0 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 15841575
- Warranty: This genuine part is guaranteed by GM's factory warranty.
More Info
Fits the following 2006 GMC Sierra 1500 Submodels:
- Base, C3, Denali, SLE, SLT, WT | 8 Cyl 6.0 L GAS, 8 Cyl 6.2 L GAS
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2006 GMC Sierra 1500 Radiator Part Number: 15077163
Product Specifications
- Replaced by: 19117219
- Item Weight: 5.80 Pounds
- Item Dimensions: 25.9 x 21.4 x 7.5 inches
- Condition: New
- SKU: 15077163
- Warranty: This genuine part is guaranteed by GM's factory warranty.
Fits the following 2006 GMC Sierra 1500 Submodels:
- Base, Denali, Hybrid, SLE, SLT, WT | 6 Cyl 4.3 L GAS, 8 Cyl 4.8 L GAS, 8 Cyl 5.3 L FLEX, 8 Cyl 5.3 L FULL HYBRID EV-GAS (FHEV), 8 Cyl 5.3 L GAS, 8 Cyl 6.0 L GAS
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2006 GMC Sierra 1500 Radiator Part Number: 15841576
Product Specifications
- Other Name: Radiator Assembly; Radiator, Radiator
- Replaces: 15252640, 15192538
- Item Weight: 12.70 Pounds
- Item Dimensions: 49.9 x 8.9 x 36.2 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 15841576
- Warranty: This genuine part is guaranteed by GM's factory warranty.
More Info
Fits the following 2006 GMC Sierra 1500 Submodels:
- Base, Hybrid, SL, SLE, SLT, WT | 8 Cyl 4.8 L GAS, 8 Cyl 5.3 L FLEX, 8 Cyl 5.3 L FULL HYBRID EV-GAS (FHEV), 8 Cyl 5.3 L GAS
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2006 GMC Sierra 1500 Radiator Part Number: 15841583
Product Specifications
- Other Name: Radiator Assembly; Radiator, Radiator
- Replaces: 15192540
- Item Weight: 10.60 Pounds
- Item Dimensions: 7.1 x 47.4 x 25.8 inches
- Condition: New
- Fitment Type: Direct Replacement
- SKU: 15841583
- Warranty: This genuine part is guaranteed by GM's factory warranty.
More Info
Fits the following 2006 GMC Sierra 1500 Submodels:
- Base, SL, WT | 6 Cyl 4.3 L GAS

2006 GMC Sierra 1500 Radiator

With a comprehensive array of OEM 2006 GMC Sierra 1500 Radiator, from fuel pumps to door handles, our website is a one-stop-shop for your needs. All our genuine 2006 GMC Sierra 1500 Radiator are backed by the manufacturer's warranty and are offered at competitive prices in the market. Rest assured, you can shop with complete confidence.

2006 GMC Sierra 1500 Radiator Parts and Q&A

Q: How to replace the radiator for the 4.3, 4.8, 5.3, and 6.0L engines on 2006 GMC Sierra 1500?
A: To install the radiator in place of the radiators, first of all remove the cooling fan and shroud and then remove the radiator outlet hose that belongs to the engine. Disassemble the oil cooler lines, when in case, remove the radiator bolts and extract the radiator. Uninstall then repeat steps in reverse order.